Makerere University School of Medicine
Núcleo de Doenças Infecciosas

Sites

xxxx

Uganda

Brazil

Administrative Core
Systems Biology Core
Clinical Core

View

TB Research Unit

The TBRU consortium includes a partnership with the following sites:

  • Makerere University School of Medicine, Kampala, Uganda
  • Núcleo de Doenças Infecciosas, Vitória, Brazil

In conjunction with Rutgers University, both sites have executed clinical trials, conducted clinical and translational research on pulmonary tuberculosis, and worked on multiple projects (CDRC 2009-2016; TBRU 1993-1999; TBRU 2014-2021; FEND-TB 2021-2026). The efforts between Rutgers University and these institutions have included work in biomarker discovery, Mycobacterium tuberculosis strain research, clinical trials of immunoadjuvants, and trials of new diagnostics for tuberculosis.

Uganda and Brazil have endemic high rates of pulmonary tuberculosis. Both sites have investigators (Dr. Moses Joloba, Dean of the Makerere School of Medicine; Dr. Rodrigo Rodrigues and Moises Palaci, Directors of the Nucleo Infectious Diseases at UFES) with a long history in TB research and expertise in immunology and microbiology. Both sites have highly proficient, skilled, well-resourced, and internationally recognized laboratories in microbiology and immunology.

Uganda

Makerere University (MU) is a research-led university with a rich history in biomedical studies. In 2008, the university implemented a 10-year Strategic Plan with a vision ‘To be a leading institution for academic excellence and innovations in Africa’. It aims to achieve this by providing innovative teaching, research, and services responsive to national and global needs.

Makerere University of College of Health Sciences
Upper Mulago Hill Road
Kampala, Uganda

MU has established Institutional Review Boards to oversee ethical conduct of research

MU has developed, operationalized, and reviews guidelines on good research practices and misconduct

Brazil

The Núcleo de Doenças Infecciosas (NDI) in Vitória, Brazil, was created in 1990 as a branch of the Social Medicine and Epidemiology Department at the Universidade Federal do Espírito Santo (UFES). It is located within UFES University’s Health Sciences campus, near the 300-bed affiliated teaching Hospital (Hospital Universitário Cassiano Antonio de Moraes – HUCAM).

Universidade Federal do Espirito Santo
Av. Fernando Ferrari, 514
Vitoria, Brazil

Clinical site for TBRU since 1994.

State-of-the-art mycobacteriology and immunology laboratories

Collaboration between the NDI and both the City and State Secretary of Health allows enrollment and follow-up of a large number of TB patients